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Version 5, 27 Mar 2022 at 8:27 AM
Monitoring N-Glycosylation is increasingly applied in the development of biopharmaceuticals and the study of diseased cells. Glycan preparation is laborious, with analytical methods lacking sensitivity. GlycoWorks RapiFluor-MS accelerates N-glycan preparation, whilst improving detection sensitivity. Repeatability and traceability are assured when paired with Andrew Alliance automation solutions.
Version 2, 27 Mar 2022 at 8:28 AM
N-glycans affect the safety and efficacy of many therapeutic proteins and are routinely monitored for the quality of biotherapeutics. Here, we present a complementary method for analyzing the complex N-glycans released from human chorionic gonadotrophin (hCG). The automated method provides a reproducible glycan profile and is suitable for commercial as well as research environments.