Genomics

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Version 1, Sep 29, 2019 9:03 AM
Gene Knockout is a technique that is fundamental to the investigation of gene function, which has been made easier and faster by the revolutionary breakthrough of CRISPR technology. OneLab provides clear step-by-step guidance on correct execution of the clonal isolation process to ensure optimal input, as well as identification of wells with single colonies. Additionally, it records each step in these procedures, enabling full traceability.
Version 1, Sep 29, 2019 9:03 AM
Library preparation aims to build a collection of DNA fragments for next-generation sequencing (NGS). A high-quality DNA library guarantees uniform and consistent genome coverage, thus delivering comprehensive and reliable sequencing data. OneLab helps you streamline and trace critical steps in your library preparation process to achieve the best possible DNA quality and purity.
Version 1, Dec 1, 2019 11:06 AM
Circulating cell-free DNA derived from diseased cells is a promising biomarker for non-invasive diagnosis and treatment monitoring. Harnessing the potential of ccfDNA involves not only an understanding of its biology and dynamics but also the standardization of isolation methods. OneLab can act as a platform to execute your ccfDNA isolation protocol, mitigating the effect of pipetting variability.
Version 1, Sep 29, 2019 9:03 AM
Phenol-chloroform phase separation followed by alcohol precipitation is a conventional method to isolate genomic DNA. A successful DNA extraction involves complete cell lysis, removal of contaminants and minimal shearing of DNA. To achieve this goal, OneLab guides you through the extraction protocol, thereby ensuring all defined conditions are fulfilled without errors.
Version 1, Dec 1, 2019 11:06 AM
Modern sequencing technology requires precise and reliable DNA sample clean-up and size-selective purification to ensure accurate and consistent data. Using the ProNex® size-selection chemistry, OneLab allows clean and error-free processing of your DNA samples with full traceability of individual pipetting actions.
Version 1, Sep 29, 2019 9:03 AM
Accurate and consistent quantitation of nucleic acids is a prerequisite for high-value applications in genomics. Fluorometric quantification provides a fast, sensitive and selective measurement of the concentration of nucleic acids in your sample. OneLab enables you to record the step-by-step execution of your sample preparation, ensuring easy and error-free processing.
Version 1, Sep 29, 2019 9:03 AM
Quantitative RT-PCR is a powerful tool to investigate gene expression. However, several challenges are encountered by scientists during sample preparation, including pipetting errors and DNA contamination. OneLab addresses these issues by providing step-by-step guidance for pipetting and traceability, so as to mitigate unnecessary waste of reagents and improved data reproducibility.