General sample prep

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Version 1, 28 Mar 2021 at 9:15 AM
Dilute-and-shoot is a simple and rapid analytical method for multi-analyte identification. Although sample preparation is minimal, it remains a critical step to ensure accurate quantitation. The protocols described here use the dilute-and-shoot approach and take advantage of the Andrew+ capabilities to automate sample preparation ensuring maximum pipetting precision and efficient mixing.
Version 1, 28 Mar 2021 at 9:15 AM
Protein precipitation is the simplest form of plasma/serum preparation. However, pipetting errors and contamination during sample preparation can impair assay sensitivity, robustness, and precision. In the following work, Andrew+ was used to prepare and extract analytes from complex biological matrices, using the Ostro sample prep plate, with subsequent LC-MS/MS analysis and quantification.
Version 1, 28 Mar 2021 at 9:15 AM
LC-MS analytical method development requires flexible and reproducible sample preparation for accurate and robust analyte quantification. The following work demonstrates the automated standard curve generation using the Andrew+ Pipetting Robot, with cloud-native OneLab Software, for accurate and reproducible LC-MS quantification of nitrosamine impurities.