Biopharma

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Version 2, 28 Mar 2021 at 9:15 AM
The task of accurately separating, identifying, and quantitating amino acids in the research, development, and commercialization of food, feed, and biotherapeutic products is challenging. To analyze released amino acids by HPLC or UPLC, Waters provides many solutions that use pre-column derivatization so that amino acids can be analyzed by optical detection.
Version 1, 28 Mar 2021 at 9:15 AM
Adequate endotoxin testing is invaluable in ensuring quality and safety. LAL assays require cumbersome sample preparation and are easily disturbed by different constituents of the sample. EndoLISA, combining solid-phase format and synthetic rFC, achieves sensitive detection of endotoxin by eliminating interfering components. It can be automated, which accelerates the test with minimal human error.
Version 2, 28 Mar 2021 at 9:14 AM
Monitoring N-Glycosylation is increasingly applied in the development of biopharmaceuticals and the study of diseased cells. Glycan preparation is laborious, with analytical methods lacking sensitivity. GlycoWorks RapiFluor-MS accelerates N-glycan preparation, whilst improving detection sensitivity. Repeatability and traceability are assured when paired with Andrew Alliance automation solutions.
Version 1, 28 Mar 2021 at 9:15 AM
The manufacturing of therapeutic IgG antibodies is a complex process that requires precise monitoring. A major issue to address in relation to IgG measurement is reproducibility. The Valita™TITER assay combined with Andrew Alliance’s automation and OneLab software provides a standardized and traceable solution for fast and accurate IgG quantitation, thus mitigating the effect of user variability.